MBP has been thought of as an essential factor for avoiding infectious complications and anastomotic dehiscence, most commonly in colon surgery. This is based upon the belief that MBP reduces the volume of solid or semi-solid contents at the time of surgery, theoretically reducing bacterial load, and the risk of intraoperative enteric spillage. MBP has become a standard of care across many surgical disciplines involving the gastrointestinal tract, including foregut surgery.

PD is a complex surgical procedure of the upper gastrointestinal tract designed to treat benign and malignant disorders of the pancreas and periampullary region. The operation involves resection of the pancreatic head and uncinate process, duodenum, and intra-pancreatic portion of the common bile duct, with reconstruction via anastomotic attachments between the pancreas, biliary tree, and stomach/duodenum to the jejunum. The operation is considered a clean contaminated case, and the major causes of postoperative morbidity include pancreatic fistula, intra-abdominal abscess formation, wound infection, urinary tract infection (UTI), and delayed gastric emptying.

Source: Thomas Jefferson University