University of Liverpool Professor, Jon Rhodes, part of the Liverpool Biomedical Research Centre (BRC), said: "Crohn's disease affects people from all over the world, but it is much more prevalent in developed countries, where a diet of low fibre and processed foods is common. There has been a rapid increase in incidence of the disease in Japan, for example, which now has more of a western processed food diet. Dietary factors and the increased numbers of E. coli in the intestine of Crohn's patients suggested to us that there could be a link between the food that we eat and the transportation of bacteria in the body."

Dr Barry Campbell, from the University's Institute of Translational Medicine, added: "This research shows that different dietary components can have powerful effects on the movement of bacteria through the bowel. We have known for some time the general health benefits of eating plantain and broccoli, which are both high in vitamins and minerals, but until now we have not understood how they can boost the body's natural defences against infection common in Crohn's patients. Our work suggests that it might be important for patients with this condition to eat healthily and limit their intake of processed foods."

Peter Laing, Head of Research and Development, Provexis, said: "In partnership with the BRC, we are hopeful that this new medical food, containing soluble plantain fibres, could help halt the progression of the disease and prevent it from returning."

Source: University of Liverpool